Abstract: A pot experiment with wheat plants (Triticum aestivum L. cv. Giza 167) grown on 2.0% or 10.0% CaCO3 in the soil was conducted to study the effect of foliar fertilization of boron, zinc and their combinations on zinc/boron ratio, elemental status and shoot growth. Growth of plants grown on low lime levels was not affected. The best treatments led to highest growth of shoots grown on soil of high lime content were 25 ppm B or 25 ppm B + 50 ppm Zn in the spray solution. Boron concentrations were increased in the shoot tissues of plants grown on both CaCO3 levels as boron or zinc was applied. Meanwhile, zinc concentrations were slightly increased when only boron was sprayed; however it decreased when combinations of boron and zinc were applied. Boron or zinc uptake by the shoots grown on low lime level was less affected compared to those grown on high lime level. Best uptake of boron and zinc was obtained by the low dose of the two elements combination (25 ppm B +50 ppm Zn). Uptake increases over control obtained by this treatment reached about 230% for boron and 650% for zinc in the plant shoots grown on high lime level. Uptake percentage of other elements by the shoots grown under lime stress conditions was higher than that of plant shoots grown under low lime level in the soil. Highest uptake of Fe, Mn, Cu, K and Ca were obtained by boron treatments alone or low dose of boron and zinc combinations, which suggested that boron stimulates metabolic functions facilitate absorption and translocation of these nutrients, especially in plants grown under lime stress conditions