Abstract: A study was conducted in strongly acidic sandy loam soil at the Potato Breeder Seed Production farm, BARI, Debigonge, Panchogar, to investigate the effect of lime and potassium on tuber yield. The tested factors were application rates of lime (0, 0.5, 1.0 and 2.0 t ha-1) and potassium (0, 60, 80 and 100 K, kg ha-1). The treatment combinations were allocated to experimental plots in Randomized Complete Block Design. Lime and potassium significantly increased tuber yield. Highest increased yield was recorded about 86.54% over control. The optimum rate of lime and potassium in acidic sandy-loam soils could be recommended for potato cultivation at 2 t ha-1 and 100 kg ha-1, respectively.