Abstract: Different climatic zones and with complex tropical patterns and crop practices favor various pest species in Pakistan, including vertebrate pests second to insect pest species. Amongst vertebrate pests, overall rodents are threatening more than any other group. Presently, in Karachi, Malir Distt., coconut plantation have been surveyed for the estimation of the extent of the rodent damage thereon. Estimation of sugarcane damage due to rat infestation at post-harvest stage in Sindh was made at four sample sites in Thatta and Sanger districts. Therefrom, samples were collected randomly and analyzed to determine the extent of damage. The damage due to rodent activity has been estimated as 15%±5 and 7.5±1.5 in coconut and sugarcane, respectively.