Abstract: The field experiment was carried out to find a suitable and economic dose of fertilizer (combination of N, P2O5, K2O and S) for potato cultivation in no tillage mulching situation. Three fertilizer packages with a control (without fertilizer) were tested. At all locations, the treatment F4 (120, 100, 120 and 20kg ha–1 N, P2O5, K2O and S respectively, out yielded the control as well as other fertilizer doses. The tuber yield pattern due to different fertilizer packages followed the same trend for all tested locations but overall performance of Shariatpur was better than Madaripur and Gopalgong. The gross return, gross margin and marginal rate of return were also found the highest in same treatment at all the three locations.