Abstract: Biochemical parameters were determined in the serum of three adult she-camels. The effects of following four treatments were studied: (I) 5 ml of isotonic saline solution, (ii) xylazine (0.25 mg/kg), (iii) xylazine (0.5 mg/kg), (iv) xylazine (0.5 mg/kg) followed by Yohimbine (0.5 mg/kg). The biochemical parameters investigated were: total proteins, albumin, globulin, A/G ratio, glucose, urea, creatinine, AST, ALT, AP, Na, K, Cl, Ca, P, Mg and Fe. Xylazine administration resulted in significant changes in glucose, urea, AST, ALT and AP values. Yohimbine administration failed to prevent or decrease the hyperglycemic effect of xylazine. Minor changes were observed in the remaining parameters.