Abstract: The effect of irrigation with industrial effluents was evaluated on growth, uptake of nutrients and yield of wheat (Triticum aestivum Giza 164) and faba beans (Vicia faba Giza 461) plants. Also, irrigation by industrial effluents in combination with vesicular-arbuscular mycorrhiza (VAM) was used as biological control to overcome the harmful effects of pollution with heavy metals. Irrigation of plants with industrial effluents led to marked changes in growth criteria depending on plant and the stage of growth. Industrial wastewater led also to marked changes in total carbohydrates and nitrogen contents in both shoots and roots. On the other hand, combination of industrial wastewater with VAM caused an increase in the total carbohydrates and total nitrogen in shoots and roots of both wheat and bean plants. The yield components in wheat and bean were significantly increased with industrial effluents, but the biochemical concentrations were different. In wheat, the carbohydrate concentrations were increased, but protein-N and total-N were decreased, however mineral content especially Zn was increased. A reverse response was recorded with VAM. The situation was totally opposite in case of bean. Generally, bean plants were more sensitive to pollution with heavy metals, than wheat plants however this influence might also be overcome using VAM