Abstract: Effect of herbal diuretic mixture (1, 2 and 3%) in drinking water and Nephrobiotic-DM protein (TSP, BUN and moisture percentage of dropping (DMP) of broilers. Non significant changes were observed on TSP values. However, BUN was significantly decreased on 5th day of phase 1 mid of lag phase and 3rd day of phase 2 indicating that both drugs have prolonged effect DMP was significantly higher on last day of the second phase. It was also significantly higher in the groups given 1.1 DM (3%) and Nephrobiotic-DM. This significant increases in the DMP indicated the efficacy of the time drugs used without harmful effects.