Abstract: The water was alkaline throughout the stretch under study. The electrical conductivity of water at Hudiara nulla was the maximum due to the input of large amounts of salts and other nutrients in thiS tributary. Dissolved oxygen contents were significantly lower at Farrukhabad nulla, Munshi hospital nulla, Baker mandi nulla and Hudiara nulla than rest of the sampling stations. These significantly low values of dissolved oxygen corresponded inversely with the metal ion concentrations in water. There were significant variations among different sampling stations for heavy metals toxicity and physico-chemical variables viz. total hardness, water temperature, dissolved oxygen, pH and electrical conductivity. The variable significance of different parameters with positive and negative partial regression coefficients at different sampling stations were due to the difference of these stations for metals toxicity levels. On the whole, both zinc and iron toxicities in water were positively and significantly dependent on water temperature while negative but significant on pH of water.