Abstract: Four wheat varieties viz. Blue Silver, Pak 81, Inqalab 91 and Kohistan 97 were crossed in a complete diallel fashion for combining ability analysis of five agronomic characters. Significant genetic variability existed for all the traits under study. The variance components attributable to both general combining ability (GCA) and specific combining ability (SCA) for grain yield, plant height and number of nodes per plant were significant. The GCA mean squares were larger than those of SCA for all the characters except grain yield. The relative magnitude of these variances indicated the preponderance of additive gene action for most of the characters. Variety Blue Silver was found to be the best general combiner for grain yield. For plant height and number of spikelets per spike, Pak 81 showed its superiority for general combining ability. Crosses Blue Silver×Kohistan 97 and Kohistan 97×Pak 81 gave markedly higher SCA values for grain yield. Selection of desirable segregants from these two crosses will be useful for improvement in grain yield.