Abstract: Cotton leaf curl virus (CLCuV) disease severity was recorded on CIM-1100, CIM-109, CIM-435, NIAB-78, NIAB-Krishma and SLS-1 cultivated in Rajanpur, Dera Ghazi Khan, Muzaffarghar, Multan and Jhang districts of cotton belt of Punjab. Three locations were selected randomly from each of the five districts and CIuCV was recorded according to a scale on a sample of 60 plants divided to those lots/replications each containing 20 plants for each variety at each location. Enviromental parameters and disease severity differed significantly among the districts and cotton cultivars. Expect significant correlation of monthly rainfall with CLCuV on NIAB-78 and relative humidity with disease severity on CIM-1100, CIM-435 and SLS-1, all other correlation were riot significant. Maximum disease severity was recorded at 40-43°C and 26-28°C maximum and minimum air temperature, 102-147 mm rainfall and 67-74% relative humidity. There was a poor linear relationship of majority of environmental variables with disease severity on most of the cultivars with few exceptions. Environmental data recorded on daily or weekly basis by sensitive sensors attached with weather stations installed at hot spots of cotton belt of Punjab is required for accurate disease forecasting.