Abstract: Wool is one of the improtant textile commodity obtained from the bodies of sheep all over the world. The wool fibers are soft, warm and flexible and made of Keratin and therefore easily colonized degraded and destroyed. Research has shown that wool is not only destroyed by Keratinophilic fungi, but two other fungal species such as Penicillium sp. and Aspergillus sp. also contribute its, degradation. In this regard, I have started experimenting to comprehend the actual agent involved into destruction of the wool fibers. The results will be published through present journal as Research advances.