Abstract: Six Newcastle disease virus (NDV) isolates were recovered from field outbreaks of the disease in and around Faisalabad. Viral isolates were confirmed by haemagglutination activity and haemagglutination inhibition test. On the basis of mean death time (MDT), intracerebral pathogenicity index (ICPI) and intravenous pathogenicity index (IVPI), two isolates were categorized as lento genic and four as misogynic. Non was velogenic. Haemorrhages were observed on body of dead embryos and urates were deposited in allantoic cavity of lento genic and misogynic group. In chicks of lento genic group lesions were observed in proventriculus, intestine and lungs, while haemorrhages were observed on proventriculus, intestine, lungs, brain and liver and spenomagly of chicks of misogynic group.