Abstract: Broiler chicks receiving 2 and 4g Norponin-S (Yucca schidigera extract) /10 kg feed did not show any untoward clinical signs and gross or histological lesions in various organs. The weekly weight gain was significantly greater in Norponin-S treated broilers than the control (P<0.001). Norponin-S had no significant influence on haemogram values of broilers. There was a general trend of lesser organ index for liver, proventriculus, gizzard, intestine, heart, testes and ovary but greater for pancreas and thyroid than the control. The study indicates that Norponin-S is a safe product for broilers and yielded better weight gain.