Abstract: Soil samples from 3-6 inches depth were collected at 8 different locations from Cholistan desert during an expedition in November 1997. Physico-chemical analysis by standard methods revealed the following information as; electrical conductivity as 211±25.63 μ S/cm, pH as 8.72±0.09, total alkalinity as 5.36±1.63, bicarbonate content 91.44±6.8 MEq/L, chloride content 1.12±0.25 MEq/L, sulphate as 212.49±23.26 MEq/L, Na as 12.12±1.66 MEq/L, K as 11.83±5.06 MEq/L, Ca as 0.62±0.097 MEq/L and Mg as 1.00±0.17 MEq/L. Carbonate and orthophosphate were not detected by the employed methods. The amount of organic matter was 1.035±0.167 per cent with total nitrogen content of 0.047±0.01 per cent. When soil samples were subjected to metal analysis by atomic absorption spectroscopy, sub-optimal levels of all four studied metals (in ppm) were found, i.e., Cu was 0.079±0.022, Fe was 1.808±0.316, Mn was 1.653±0.212 and Zn was 0.0363±0.007. These lower levels of essential metals indicate lower demands of these metals by the desert vegetation.