Abstract: All the tested insecticides at their recommended doses significantly reduced the insect pest complex of Cotton as compared to that of control. Tamaron 600SL (Methamedophos) ranke Ist by giving more than 85 percent mortality of the sucking insect pests (white fly, thrips, jassids, and mites). Furry 100EC (Zectacypermethrin) was the least effective insecticide with less than 70 percent killing of the test insects. Against bollworms, Pyrethroids reduced 85.95 percent of the pest infestation, while Curacron (Profenofos) 500EC, an organophosphate could only reduced 61% of boll infestation. However, compared to check all the insecticides in reducing the pest infestation were statistically significant at alpha 0.05. Six sprays of Polytrin-C (Curacron+Cypermethrin) 440EC, at 14 days interval gave maximum yield of solution.