Abstract: Colchicine at various concentration was given to the apical buds of maize (Zea mays L.) Plants, in order to induce tetraploidy for meiotic studies. Highly irregular meiosis in the C1 generation was revealed. These meiotic abnormalities increased pollen sterility which lead to a lower seed setting. In the C2 generation the occurrence of bivalents has increased and that of multivalents has decreased. Restoration of meiotic regularities, pollen fertility.