HOME JOURNALS CONTACT

Pharmacologia

Year: 2013 | Volume: 4 | Issue: 2 | Page No.: 77-81
DOI: 10.17311/pharmacologia.2013.77.81
Anti-obesity and Hypolipidemic Activity of Methanol Extract of Tecoma stans Flowers on Atherogenic Diet Induced Obesity in Rats
S. Kameshwaran, C. Jothimanivannan, R. Senthilkumar and A.R. Kothai

Abstract: Objective: Tecoma stans (Bignoniaceae) is conventionally used for a variety of treatments and also in the cases of arteriosclerosis and circulatory irregularities. Hence, the present exploration was intended to assess the potential effect of Methanol Extract of flowers of Tecoma stans (METS) on obesity and hyperlipidiemia on Atherogenic diet induced obese rats. Methods: METS at the doses of 100 and 200 mg kg-1 were administered along with atherogenic diet for a period of 42 days. Parameters such as body weight, body temperature, serum lipid profiles, SGOT and SGPT were evaluated. Results: METS at the dose of 200 mg kg-1 significantly (p<0.001) corrected the altered parameters, similar to that of standard drug sibutramine (2 mg kg-1). Conclusion: From the observations of the study performed, it could be predicted that Tecoma stans flower extract exerted significant anti-obese and anti- hyperlipidemic effects in rats fed on Atherogenic diet.

Fulltext PDF Fulltext HTML

How to cite this article
S. Kameshwaran, C. Jothimanivannan, R. Senthilkumar and A.R. Kothai, 2013. Anti-obesity and Hypolipidemic Activity of Methanol Extract of Tecoma stans Flowers on Atherogenic Diet Induced Obesity in Rats. Pharmacologia, 4: 77-81.

Related Articles:
© Science Alert. All Rights Reserved