Abstract: In order to improve the rooting performance of shea stem cuttings to enhance the establishment of shea plantation, an investigation was carried out in 2003/2004 at the Cocoa Research Institute of Ghana Substation, Bole in a polythene propagator. The propagating structures for the experiment were kept under a shade net (50% shade) to create a microclimate for the cuttings. The treatments employed were leaching, different growth media and hormone application. Rejuvenated (coppiced cuttings) shoots that were not leached (not dipped in water) gave significantly higher rooting than the leached cuttings while Seradix 3 powder applied cuttings produced significantly higher (p<0.05) rooting than the control. Significantly high in number, more developed and longer roots per cutting were recorded for the rice husk medium than the sand and sand+top soil (1:1) media. The biochemical analysis significantly recorded high levels of sugar and phenol for cuttings that were not leached in water. The results of this study demonstrated that rice husk medium was the best for rooting shea cuttings.