Abstract: Desmodium gangeticum (DG) aqueous extract was investigated for its wound healing potential on different experimental models of wounds in rats. The aqueous extract of aerial part of DG, in powdered form was incorporated in ointment (10% w/w dried powder in simple ointment base) and was evaluated for wound-healing potential in an excision, incision and dead space wound model in rats. The DG ointment showed significant responses in all three-wound types tested when compared with the control group. The effect produced by the DG ointment, in terms of wound contracting ability, wound closure time, tensile strength of the wound, regeneration of tissues at wound site were comparable to those of a standard drug povidone iodine ointment.