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Journal of Medical Sciences

Year: 2013 | Volume: 13 | Issue: 6 | Page No.: 401-409
DOI: 10.3923/jms.2013.401.409
Phytochemical Evaluation and in vitro Free Radical Scavenging Activity of Cold and Hot Successive Pseudobulb Extracts of Medicinally Important Orchid Flickingeria nodosa (Dalz.) Seidenf
G.S. Nagananda, Nalini Satishchandra and S. Rajath

Abstract: Flickingeria nodosa (Dalz.) Seidenf is an epiphytic orchid with pseudobulbs which has medicinal importance in traditional system of medicine. In charak samhita it is known as Jeewanti which means life promoter. Based on its importance the present work was designed to evaluate its phytochemical constituents and free radical scavenging activity of pseudobulb cold and hot successive extracts. The phytochemical secondary metabolite screening of extracts revealed the presence of alkaloids, flavonoids, phenols, phytosterols and total antioxidant components. Based on the quantitative estimation studies it revealed that extracts have a good amount of secondary metabolites. The cold and hot successive extracts were subjected to free radical scavenging activity on DPPH, ABTS radical cation decolorization assay, Hydroxyl radical scavenging activity and Nitric oxide scavenging activity. The result revealed that the highest DPPH scavenging and ABTS scavenging activity was seen in the cold acetone extract, hydroxyl radical scavenging activity was more with hot chloroform extract and nitric oxide scavenging activity was more with cold water extracts. The plant can be a source material to herbal drug industry since it is a reservoir of phytochemical components that can be used for the development of therapeutic phytomedicine for the therapy and treatments.

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How to cite this article
G.S. Nagananda, Nalini Satishchandra and S. Rajath, 2013. Phytochemical Evaluation and in vitro Free Radical Scavenging Activity of Cold and Hot Successive Pseudobulb Extracts of Medicinally Important Orchid Flickingeria nodosa (Dalz.) Seidenf. Journal of Medical Sciences, 13: 401-409.

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