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Journal of Medical Sciences

Year: 2008 | Volume: 8 | Issue: 2 | Page No.: 118-124
DOI: 10.3923/jms.2008.118.124
Non-Invasive Indicators for Outcome in Children with Dilated Cardiomyopathy
Ranya A. Hegazy, Rasha I. Ammar and Mona F. Ezz El Deen Saleh

Abstract: The present research aimed at defining simple prognostic indicators for children suffering DCM. A retrospective analytic study was conducted that included 284 pediatric patients diagnosed with DCM and 112 age and sex matched children as controls. All included subjects underwent; twelve lead-ECG; Holter recording and transthoracic Doppler echocardiographic examinations were carried out in all patients. Statistical Package for Social Science (SPSS) version 9.0 was used for analysis of data. Poor outcome indicators identified by logistic regression analysis included longer disease duration, higher P-wave dispersion, bigger LVEDD, lower fractional shortening and presence of mitral regurge. Risk factors identified from 24 h ECG monitoring were higher maximum and minimum were higher maximum and mean heart rates and presence of nonsustained ventricular tachycardia. Cox regression analysis, identified bigger LVEDD, lower FS% and presence of non sustained VT as predictors of bad outcome. We conclude that LVEDD, FS%, MR, non sustained ventricular tachycardia and higher maximum and average heart rates on ambulatory ECG monitoring are prognostic indicators for outcome in children with DCM. P-wave dispersion is higher among patients with poor outcome and may carry prognostic significance that will need further evaluation. QT dispersion has no prognostic significance in children with DCM.

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How to cite this article
Ranya A. Hegazy, Rasha I. Ammar and Mona F. Ezz El Deen Saleh, 2008. Non-Invasive Indicators for Outcome in Children with Dilated Cardiomyopathy. Journal of Medical Sciences, 8: 118-124.

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