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Journal of Medical Sciences

Year: 2007 | Volume: 7 | Issue: 8 | Page No.: 1330-1334
DOI: 10.3923/jms.2007.1330.1334
Influence of Maternal Anthropometric Measurements and Serum Biochemical Nutritional Indicators on Fetal Growth
Manal A. Mohsen and Hanaa A. Wafay

Abstract: This study aims to assess mother weight, height and body mass index (BMI = weight in kg/height in m2) as well as maternal and cord blood prealbumin, albumin, retinol binding protein, transferrin and fibronectin and their impaction on fetal growth. The study included 54 pregnant women at delivery with their corresponding full term newborns. They were chosen to be free of any medical or obstetric problems that may interfere with intrauterine growth and development. Newborn body weight, length, head circumference, arm circumference, chest circumference and Ponderal Index (PI = weight in grams/length in cm3) were recorded. Serum albumin, prealbumin, retinol binding protein, transferrin and fibronectin in maternal and cord blood were evaluated using radial immunodiffusion kits. Cases were put into two groups: low birth weight equal to or less than 2.5 kg (n = 24) and control above 2.5 kg (n = 30). In low birth weight group, the correlation between maternal weight and neonatal birth-weight, PI and cord fibronectin was significantly positive. It was negative between maternal body weight and neonatal length, head and chest and arm circumferences. Correlation between maternal BMI and neonatal weight, cord blood albumin and fibronectin was significantly positive. It was negative between BMI and neonatal length, PI, head and chest and arm circumferences. In both studied groups, maternal height positively correlated with neonatal weight. While maternal albumin and fibronectin were significantly lower in low birth weight group, prealbumin, retinol binding protein and transferrin were not. Maternal albumin positively correlated with each of the neonatal length, head and chest and arm circumferences in low birth weight group. Maternal fibronectin positively correlated with each of the neonatal length, PI and cord blood fibronectin and negatively correlated with each of the neonatal head and chest and arm circumferences in low birth weight group. In conclusion, mother underweight and low BMI reduce newborn weight. Newborn length and head, chest and arm circumferences are negatively affected with maternal hypoalbuminemia. While low fibronectin reduces newborn body length and PI, low prealbumin, retinol binding protein and transferrin have no influence on fetal growth.

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How to cite this article
Manal A. Mohsen and Hanaa A. Wafay, 2007. Influence of Maternal Anthropometric Measurements and Serum Biochemical Nutritional Indicators on Fetal Growth. Journal of Medical Sciences, 7: 1330-1334.

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