Abstract: From September to November 2006, blood samples from 200 HIV/AIDS individual who are attending the Plateau State specialist Hospital, Jos were screened for malaria parasites, level of malaria parasitaemia and albumin level response to the infection. Twenty healthy volunteers albumin levels were measured and used as the normal range values. Of the 200 HIV/AIDS patients examined, 64 (32.0%) had Plasmodium parasites, while 136 (68.0%) who had no Plasmodium parasite were used as controls. The prevalence of malaria parasites in the age grouping revealed a significant difference, while a no significant difference was observed in the degree of parasitaemia among the age grouping. Of the 200 HIV/AIDS examined, 78 (39.0%) of them are farmers and this group also has a high rate of Plasmodium parasitic infection 30 (15%). Only P. falciparum (30%) and P. malariae (0.5%) with a mixed infection of P. falciparum and P. malariae (1.5%) were seen. There was a significant difference in the albumin level between the infected and the control. In conclusion, albumin level in the malaria-HIV/AIDS positive individuals is lower than in the HIV/AIDS positive. Albumin level can be used as a prognostic marker for disease severity and progression in HIV/AIDS.