Abstract: Measurement of human head or cephalometry is used in identification, forensic medicine, plastic surgery, orthodontics, archeology and examine the differences between races. This investigation was undertaken on 800 young women (18-25 years old) to determine the head and face phenotypes among them in two aborigines of Sistani (Fars) and Baluchi who were resident in southeast of Iran. In this study cephalic and prosopic indices were determined by classical cephalometric method. Means and standard deviation of cephalic indices were 78.4±4.15 and 81.94±4.99 and prosopic indices were 83.22±4.02 and 84.86±5.15 in Sistani and Baluchi subjects, respectively. Based on the cephalic index, the dominant and rare head types in Sistani group was mesocephalic (41.3%) and hyperbrachycephalic (6%) and in Baluchi group was brachicephalic (42%) and dolichochephalic (5.5%), respectively. Furthermore, according to the prosopic index, the dominant and rare face type among Sistanis were euryprosopic type (50.8%) and hyperleptoprosopic (0.5%) and in Baluchi group were euryprosopic (37%) and hyperleptoprosopic (2.5%), respectively. This research showed that differences in terms of head and face type indices between these two groups were statistically significant. Based on this cross-sectional study, it seems that there is differences between the aforementioned groups.