Abstract: The association of erythrocytes and leukocytes count and haemoglobin level with cigarette smoking was studied and results were compared with non-smokers. The erythrocytes count in smokers was significantly high (p < 0.0005) compared with the non-smokers. The leukocytes count was significantly higher (p < 0.02) in non-smokers compared with the smokers. The difference in haemoglobin level was also significant (p > 0.05) between smokers and non-smokers, smokers being having low level of Hb. The number of cigarettes smoked per day and length of smoking showed the negative correlation with erythrocytes count and positive correlation with leukocytes. The haemoglobin also showed the negative correlation with the number of cigarettes per day (r = -0.57) and period of smoking (r = -0.46).