Abstract: A study was conducted at the farm section of the Department of Fisheries Technology, Federal Polytechnic Nekede, Owerri in 2012. Factorial design of five treatments of cassava peel meal at 0, 25, 50, 75 and 100% graded level were formulated. The cassava peel meal was sundried for 48 h, ground and added to the feed fed to 150 fingerlings of Oreochromis niloticus into 10 tanks in triplicates and fed twice daily at 5% body weight for 60 days. The result shows that fish fed with 100% cassava peel meal had the highest mean weight gain of 10.46±0.01 and specific growth rate of 1.23±0.04. The second best result was shown in fish fed with 75% cassava peel meal with weight gain of 9.93±0.03, Feed Conversion Ratio (FCR) of 1.75±0.04 and specific growth rate of 1.24±0.02. The poorest result was shown by fish fed 25% cassava peel meal with the lowest survival rate, weight gain, feed intake and specific growth rate, respectively. This connotes that diet with 100% fed graded level of sundried cassava peel meal can best be utilised at a ratio of 75 to 15% CPM and second best diet with 75% fed graded level of sundried cassava peel meal could also be utilized at 11.25% inclusion due to its survival rate parameter over the best. Moreover, this proportion should be utilised for improve growth of Nile tilapia (Oreochromis niloticus) for profit maximization.