Abstract: The present study was established to evaluate the potential of insect growth regulator on the growth and development of Tribolium confusum Azadirachtin, a neem derivative which considered as insect growth regulator due to its chitin inhibitor activity was tested topically at four doses (0.5, 1, 1.5 and 2 μg insect-1) on adults of Tribolium confusum (Coleoptera: Tenebrionidae) and first evaluated on fecundity, hatchability and viability of eggs, longevity and morphometric of oocytes. Results show that the compound reduces the longevity and the fecundity. Generally, treatment with azadidrachtin affected growth and development of oocytes and egg-viability as shown by calculating the number of oocytes per ovaries and the size of basal follicle. The width of the follicle has not been affected significantly by these treatments. In the second group of experiments, this IGRs don’t induce significant reduction in percentage of hatchability, the hatching rate of eggs laid by F1 females was not affected by the treatment (F = 2.86, DF = 99, p = 0.5) but it affect very significantly the viability rate of eggs laid by first female generation F1 (F = 7.5, DF = 99, p>0.0001). However, the azadirachtin lengthened very significantly the total duration of life cycle. Duration of the embryonic and post embryonic development of eggs laid by treated female increase when the concentration varied from 0 to 2 μg μL-1. This data confirm the efficiency of growth regulators derived from neem plant, on the development of stored product insect pests.