Abstract: In this trial, some aspects of the biology: oviposition, development, survival, fecundity and damage cause by Sitophilus oryzae on stored rice and the control of the weevil, using leaf powders of Ocimum gratissimum and Vernonia amygdalina were studied under ambient laboratory conditions (temperature range 28-30°C and 60-77% relative humidity). Toxicity tests consist of exposing adult weevils to various levels of 0, 1, 2, 3, 4 and 5 g per 20 g grain. The leaf powders were admixed with rice grains. The results showed that the tested leaf powders have insecticidal activities. Based on the percentage mortality, number of egg laid, number of emerged adult, percentage weight loss and percentage punctured grain. The trial also revealed that Ocimum gratissimum was more effective than Vernonia amygdalina as stored grain protectants at all dosage level of application.