Abstract: The key significance of this study is the development of a database termed as Oncvir. The resource is developed using Hypertext Preprocessor, Hyper Text Markup Language and JavaScript as front-end and MySQL as backend. OncVir mainly in-houses information on nucleotide sequence, protein sequence and protein structure information’s of human oncoviruses. Oncoviruses are those categories of viruses which assist in the immortalization of the cancer cells. The key classification factor of these viruses is its genetic material either DNA or RNA. OncVir is a database which comprehends the information of human oncogenic viruses such as Hepatitis B Virus, Human Papilloma Virus; Kaposi's Sarcoma-associated Herpes Virus, Epstein-Barr virus, Merkel cell polyomavirus, Hepatitis C virus, Human T-lymphotropic virus and Human Cytomegalovirus. This knowledgebase includes information from literature and other public available databases. The database is accessible to keyword searching via., simple and advanced options. It integrates about 215 nucleotide sequence records, 158 protein sequence records and 68 structural information associated with oncoviruses. It also facilitates additional facility to users to submit their sequence and structural data using tools such as OncSeq and OncTer, respectively. Moreover, additional information including description of viruses with illustrations, overview about the database, new events and updates are also available. In short Oncvir serves as a single access point for substantial and multitudinous information about human oncoviruses.