Abstract: Intercropping cotton and wheat is a new farming system in Egypt. The main objective of this research was to investigate the response of sole and relay intercropping cotton and wheat to the effect of sowing dates and ridge width on cotton yields in Abo Hussein Village, Abo Kebeer district, Sharkia Governorate, Egypt. The experiment was carried out in a strip plot design with four replications. The vertical plots were occupied with three sowing dates. The horizontal plots were assigned to three ridge width. Sowing on 15th March significantly affected (p<0.05) number of days to first flower opening and plant height of sole and relay intercropping cotton and number of fruiting branches/plant, number of opened bolls/plant, boll weight, seed cotton yield per plant and feddan and lint cotton yield/fed of sole cotton and resulted in the highest values in both seasons. Sowing relay intercropping cotton on 1st April significantly affected (p<0.05) number of fruiting branches/plant, number of opened bolls/plant, boll weight, seed cotton yield per plant and feddan and lint cotton yield/fed and produced the highest values in both seasons. Sowing sole or relay intercropping cotton on wide ridges significantly affected all studied traits and produced the highest values in both seasons. It can be concluded that, in order to maximize seeds and lint cotton yields/fed of sole cotton, it must be sown in 15th March on ridges with width of 100 cm. However, for maximization of seeds and lint cotton yields/fed of relay intercropping cotton, it must be sown in 1st April on ridges with width of 100 cm.