Abstract: Correlation analysis of wool yield at age of one year in Wan line Angora rabbits using microsatellite DNA markers was studied. The results showed that the average number of alleles per locus was 4.5 (from 3 to 6) in Wan line Angora rabbits. The mean heterozygosity and the average polymorphism information content were 0.680 (from 0.630 to 0.721) and 0.642 (from 0.559 to 0.705), respectively. The relationships were not significant between Sat4, Sat13, So144 loci and wool yield (p>0.05). The relationship was significant between Sol33 locus and wool yield (p<0.05) and wool yield of genotype AD and BD were significantly higher than that of the other three genotypes which did not have gene D (p<0.05). This may indicated that the gene D could synergize wool yield of Wan line Angora rabbits.