Abstract: We report a child with excessive hypereosinophilia caused by excessive ingestion of royal jelly and honey. A 10-year-old boy was admitted with the complaint of fatigue, anorexia and nausea and weight loss during 20 days. Clinical findings were completely normal except allergic rhinitis. Laboratory examinations revealed that white blood cell count was 78.300 mm-3 including 90% as eosinophil, serum IgE was 1193 IU mL-1, eosinophilic cationic protein was 200. Laboratory examinations including immunoglobulin levels, collagen vascular disease parameters, serum vitamin B12 and folic acid levels were normal. Parasitological examinations including microscopic and serological were negative as well. We thought that he had idiopathic hypereosinophilic syndrome, however detailed history from his mother demonstrated that our patient had been received excessive amount of honey and royal jelly regularly during one month prior of is admission. He had positivity to Artemisia, Alternaria, Cat Fur and Dog Hair with skin test. We have no detected positive results for hymenoptera venom. We stopped receiving the royal jelly ingestion and started a therapy for allergic rhinitis. His eosinophil count dramatically decreased and clinical findings improved. At 6th months of follow-up period, clinical and laboratory findings were normal. This case suggests the importance of the public training about the excessive and inefficient usage of these alternative medicine approaches.