Abstract: The examination of fresh water fishes captured in the Sange and Leb mbass rivers (affluent of Nkam at Yabassi and Sanaga at Edea, respectively) in Cameroon, revealed the presence of three new species of Myxosporean of the genus Myxobolus Butschli, 1882 of which the complete description is given in the present study. Myxobolus bouixi sp.n., a gill parasite of Chrysichthys nigrodigitatus (Bagridae), forms subspheric spores that measure 11.2 (10.8-12) μm long H 10 (9.5-10) μm broad; the polar capsules measure 4.4 (4-5) H 3.1 (3-3.5) μm and contain 5 to 7 coils of polar filament each. Myxobolus sangei. sp.n., parasite of gills, kidneys and skin in Brycinus macrolepidotus (Characidae), forms ovoid spores measuring 10.1 (9 -10.5) μm H 6.2 (6-6.8) μm; its polar capsules are unequal and measure, respectively 6.2 (5.7-7) H 2.2 (2-3) μm for the larger and 4.8 (4-5.5) H 1.7 (1.5-2) μm for the smaller. Myxobolus pethericii sp.n., parasite of the gills, fins, eyes, stomach, liver, intestine, operculum and kidneys of Ctenopoma petherici (Anabantidae) forms ovoid spores with a broader anterior end and measuring 12.6 (12-14) H 7.0 (6.5-7.8) μm. Its polar capsules measure 5.3 (5-6) H 1.8 (1.5-2) μm.