Abstract: The research work deals with the examination of the dissolution of aluminum from low grade bauxite of pail deposits (Khushab) with different penicillium strains. X-ray diffraction data indicated the presence of silicate and aluminosilicate minerals. Scanning electron microscopy and electron disperse X-ray analysis showed the presence of aluminum iron silica and titanium. Decrease in pH in the range of 3.40 was observed in liquid growth media inoculated with Penicillium strains (Penicillium simplicissimum and Pinicillium sp. UAF1) due to the production of organic acids. About 4.6 g l-1 Al2O3 was solubilized having bauxite pulp density 5%.