Abstract: A field experiment was conducted to study the effects of S, Zn and B supplied from chemical fertilizers and poultry manure on yield and nutrient uptake by rice (cv. BRRI Dhan-30). There were ten treatments:- T0, T1, T2, T3, T4, T5, T6, T7, T8 and T9. The rate of different nutrients were 100 kg N ha‾1 from urea, 30 kg P ha‾1 from TSP, 60 kg K ha‾1 from MP, 20 kg S ha‾1 from gypsum, 2 kg Zn ha‾1 from zinc oxide, 1 kg B ha‾1 from borax and 4 t poultry manure ha‾1. The experiment was laid out in randomized complete block design with 3 replications. The different nutrients significantly increased plant height, effective tillers hill‾1, filled grains panicle‾1, 1000-grain weight, grain and straw yields of rice. The highest grain yield of 4850 kg ha‾1 was obtained when S, Zn and B were applied together with NPK fertilizers (T8) which was comparable to the yields obtained when S, Zn or B were applied singly or in combination of two with NPK fertilizers (T2, T3, T4, T5, T6 and T7) and also with the application of poultry manure with reduced NPK application (T9). The concentrations and uptake of N, P, K and S by grain and straw were higher when poultry manure was used as a source of S, Zn and B with reduced amount of NPK(T9). It appears that application of S, Zn and B along with NPK is essential in this soil to get maximum yield of BRRI Dhan-30. If poultry manure can be applied @ 4 t ha‾1 the use of NPK can be reduced and S, Zn and B fertilizers may not be needed.