Abstract: Combined application of chemical fertilizer with farmyard manure increased the ears m -2 and grains per ear than alone application of organic or inorganic fertilizer to wheat variety Ghaznavi under the agro-climatic conditions of D.I.Khan, NWFP, Pakistan however both parameters i.e. ears per emerged seedling and grains per ear remained lower than the predicted yield in Ayah No. 261 of Surah Al-Baqrah of The Holy Quran. This variety produced the grain yield of 5.5 t ha -1 when fertilized with 20 t ha -1 FYM + 138 kg P2O5 t ha -1. Unfortunately this grain yield is far below than the grain yield (Y=axb) predicted in The Holy Quran which comes about 70 t ha -1. Therefore, it is suggested for the agricultural intellectuals to evolve varieties and agronomic techniques to achieve the grain yield predicted in The Holy Quran.