Abstract: The efficacy of five different insecticides i.e Confidor, Temik, Nuvacron, Asomido and Thiodan was compared against the whitefly on two cotton varieties,CIM-240 and CIM-448. Higher population densities of whiteflies observed on CIM-240. The effectiveness of insecticides vary with each other, however the most effective for both varieties is Thiodan and Asomido. Confidor and Temik were not significantly effected against whitefly. While in case of Nuvacron, there is a fluctuation in two varieties.