Abstract: In this study, the synthesis and application of some new disazo disperse dyes derived from 2-chloro-4-methylaniline and 3-aminophenol on nylon 6 fabric are described. The dyes were synthesized via diazotisation of 2-chloro-4-methylaniline using sodium nitrite in an acid (H2SO4) medium and coupling the diazonium salt solution produced with 3-aminophenol to give an intermediate azo compound. The amino azo intermediate was subjected to further diazotisation reaction and coupling with 1-naphthylamine, 3-chloroaniline, 4-chloroaniline, 4-hydroxybenzoic acid, 1,3-dihydroxybenzene and 2-chloroaniline to afford the six disazo disperse dyes. The dyes were characterized by spectral methods (IR, NMR and UV-visible). The results of the fastness tests showed that the light, rubbing and washing fastness of the nylon dyeings using the pressure dyeing method were higher compared with those obtained through normal dyeing method. The results of the study, thus showed that the fastness performance of disperse dyes on nylon fibre could be enhanced by using the pressure dyeing method.