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Journal of Applied Sciences

Year: 2015 | Volume: 15 | Issue: 3 | Page No.: 582-587
DOI: 10.3923/jas.2015.582.587
Sentinel Lymph Node Detection Using Methylene Blue in Iranian Patients with Early Stage Cervical Cancer
Soheila Aminimoghaddam, Leila Shadman, Raziyeh Sadat Hashemi, Zahra Mohammadi and Fatemeh Mahmoudzadeh

Abstract: Cervical cancer is one of the most common diseases in women and is associated with high mortality. The aim this study is to evaluate the feasibility of Sentinel Lymph Node (SLN) detection in patients with cervical cancer using the methylene blue dye. Patients in the early stages of cervical cancer were enrolled in this study. Methylene blue, 4 mL, was injected into the cervical peritumoral area in 24 cases. Surgically removed lymph nodes were examined by pathology for the blue lymph nodes that were considered as SLNs. Sensitivity and specificity of this test are, respectively 89 and 83%. Detection rate based on the different nodes with the highest rate of 37.5% was observed in obturator. Various studies have shown that concurrent use of methyl blue method has the highest rate of SLN identification.

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How to cite this article
Soheila Aminimoghaddam, Leila Shadman, Raziyeh Sadat Hashemi, Zahra Mohammadi and Fatemeh Mahmoudzadeh, 2015. Sentinel Lymph Node Detection Using Methylene Blue in Iranian Patients with Early Stage Cervical Cancer. Journal of Applied Sciences, 15: 582-587.

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