Abstract: Overall aim of this research is to compare the influence of Chief Executive Officers' nationality in Canadian and Russian enterprises based in China on organizational structure and design, on cultural and corporative management and on innovation (including business intelligence and competitive intelligence). Thus, from the abovementioned point of view representatives of three different business cultures (Canadian, Chinese and Russian) are compared in this study. After a review of extant literatures in organizational structure and design, cross-cultural management, innovation, business intelligence and competitive intelligence, a list of 15 variables (including Centralization, Formalization, Coordination, Delegation, Administrative Organization, Organizational structure and Design, Family, Eiffel Tower, Guided Missile and Incubator, Innovation, Business Intelligence, the Competitive Intelligence and Liaison Team) was compiled and employed in a questionnaire survey. In total, 246 employers from 181 Canadian enterprises based in China and 247 employers from 193 Russian enterprises based in China were interviewed. The analysis includes reliability analysis and Kruskal-Wallis tests (using Statistical Package for the Social Sciences software). The results show significant differences in the influence of leaders’ nationality on the 15 variables and reveal advantages and disadvantages of different business cultures. The results of the present research could help international enterprises to select Chief Executive Officers in order to find better solutions to current problems in the organization.