Abstract: This study constructs theoretical model of relationships among safety manager behavior, job insecurity atmosphere, counterproductive work behavior and quality performance based on counterproductive work behavior perspective, safety manager behavior includes management behavior and design behavior, focuses on the moderating function of safety manager behavior. In view of research object and industrial characteristics, this study sets manufacturing enterprises as research objects, uses questionnaires to obtain paired sample data of senior and middle managers-employees, adopts hierarchical regression analysis methods and constructs hierarchical regression models to empirically expound relationships among safety manager behavior, job insecurity atmosphere, counterproductive work behavior and quality performance, results show that job insecurity atmosphere has U-shaped effect on counterproductive work behavior, counterproductive work behavior has a significantly negative effect on quality performance, safety manager behavior (management behavior and design behavior) regulates relationships between job insecurity atmosphere and counterproductive work behavior.