Abstract: In order to address groundwater resource sustainability, a conceptual three-dimensional, transient and anisotropic groundwater flow model comprising of six model layers was established to simulate the regional groundwater flow in the multilayered aquifer system of Yuncheng Basin of Northern China. Investigations indicate that the groundwater of Yuncheng Basin is extremely prone to over-exploitation and requires some quick and stringent attentions. The mean annual precipitation recharge, surface water discharge, irrigation infiltration and groundwater abstraction of sub-catchments of Yuncheng Basin are some of the parameters incorporated as input variable data. The model indicates that current well extraction rates are significantly less than annual groundwater recharge to the Basin. A model result for several scenarios tested by calibration and by adjustment of parameters like the hydraulic conductivity and storage yield indicates that extraction rates will be less than groundwater input to the Basin.