Abstract: Coronary artery disease still remains the main cause of death. The existence of silent myocardial isocheim emphasized the need for All-day real-time monitoring. Therefore patient monitoring during normal activity has become increasingly important as a standard preventive craniological procedure for detection of cardiac Arrhythmias, transient ischemic episodes and silent myocardial ischemia. This paper deals the design and implementation of a Dual-mode, (700 m) Wireless Real-time Arrhythmias monitoring and Auto-warning System. The system consists of slave node, and master node with a PC-based Application user interface. The system operates at the license-free open frequency band 915 MHZ. The slave node is a DSP-based smart board carried by the patient; it acquires two channels of full-spectrum ECG, stores samples on a Flash memory capable of handling 1GBits of data, compress and transmits a digitally-processed cardiac heart signal each time with detected QRS synchronous pulses as transmission data packet. The master node is responsible for receiving, decompressing, and analyzing the transmitted data packets. The SRWF-501F915 integrated module realizes the data transmitting and receiving. The developed system can be configured as master-slave or Stand-Alone topology.