Abstract: In this study, soil samples for isolation of heavy metal resistance fungi were collected from different distance of Electric Meter manufactory in Second Industrial City, Riyadh, Saudi Arabia. Soil samples were analyzed chemically for heavy metal concentrations, total soluble salts and pH and mechanically for composition of soils. Saturation percent were determined also. Eighteen fungal isolates were grown in 10 mM concentration of either lead or copper ions. Aspergillus was predominant and represented by 6 species. Fusarium was represented by 4 species. Mucor was represented by 3 species. Penicillium was represented by 2 species. While Alternaria, Cephaliophora, Eurotium were represented by one species each. The intraspecific variability in growth response to Pb2+ and Cu2+ on agar and liquid culture was studied among isolated fungi. The growth rate of some fungi isolated on solid media was less sensitive to addition of lead or copper than biomass production in liquid culture.