Abstract: This study analyses technical efficiency of wheat growing farms in Southeastern Anatolia in Turkey. Data were collected from farms through a questionnaire study carried out following 2000-2001 growing season. Analysis was accomplished in two steps. In the first step, technical efficiency scores were calculated using an input oriented Data Envelopment Analysis (DEA). In the second step, Tobit regression analysis was used to identify determinants of technical efficiency. Results indicate that there is considerable scope for cost reduction in wheat farming in the Region. Main determinant of technical inefficiency was determined to be land fragmentation.