Abstract: Assessment to the investigated emerging sensor technologies indicates that the capacitive Microelectro-mechanical System (MEMS) pressure sensor has the highest potential used for the development of tire Pressure Monitoring System (TPMS). The potential owes to its robustness, small size and low power consumption, besides fitted well in total electronic system integration. This study describes the basic configuration, operating principle and experimental results of MEMS sensor for the development of TPMS. In addition, the application performance and experimental set up of the sensor are also discussed in this paper. Input and output pins configurations of the MEMS sensors at both standby and measured modes are studied, in order to relate to their unique construction. The threshold check is used by the tire pressure monitoring system through sensed signal extracted the data acquisition environment of the MEMS sensor. This study provides preliminary insight of using MEMS pressure sensor in a TPMS.