Abstract: Experiments were conducted aft Latif Experimental Farm, Sindh Agriculture Univeresity, Tandojam, Pakistan, to study the effect of water stress (different irrigation frequencies) on growth, yield and oil content of sunflower variety Hysun-33. The experiment was laid out in randomized complete block design with five water stress treatments replicated four times having plot size of 15 square maters. The result revealed highly significant differences for all the growth, yield and oil content characters. Water stress treatments comparison describes that four regular irrigations with 10-days interval upto physiological maturity and first irrigation after 40-days of sowing produced significantly tall plants, thickened stems, early flowering and maturity, big sized heads bearing maximum seeds, higher seed index and yield and oil content, followed by three irrigations at the interval of 15 days and first irrigation after 45 days of sowing.