Abstract: The field experiment was laid-down in farmers` saline fields near Sindh Agriculture University, Tandojam compus, to determine the effects water depletion on water infiltration rate, salt behavior, and leaching requirements in saline soil. The experiment consisted three soil moisture depletion (SMD) levels of 30, 50 and 80% on available soil moisture. The pre-project soil Physical and Chemical properties were examined which showed that the soil had clay loam texture for 0-90 cm depth. The bulk density of the soil was 1.25 g/c3 with permanent wilting point 13.5 percent soil moisture. The composite profile sampling for pH ranged between 8.0 to 8.5, ECe 5.7 to 5.9 m.mhos/cm, SAR 9 to 11 and ESP 10.8 to 13.2. The results of the experiment showed that the infiltration rate initially was higher in all the fields, but it decreased sharply and became constant after few hours. However, 80 percent SMD having dry soil due to water stress condition produced cracks and recorded maximum infiltration rate during first 20 minutes then gradually decreased and became constant after 2-3 hours. This trend of infiltration rate was also observed for the other moisture depletion levels as well. In this study the total amount of water applied under 30, 50 and 80 percent soil moisture depletions was 822, 644 and 529 mm and salts leached were 25 and 15.30 meq/l under excess (30 percent SMD) and adequate (50 percent SMD) levels receptively. It is recommended that saline soils should be irrigated at the rate of 50% SMD. But, for the quick and satisfactory salt leaching the water should be incorporated at the rate of 30% SMD. For satisfactory salt leaching practice it may take four months or greater period.