Abstract: Almond of Argania spinosa and Zygophyllum gaetulum moisture sorption isotherms were determined within the range of 0.1-0.9 water activity at three temperatures (30, 40 and 50°C), using saturated salt solutions dynamic method. Sorption isotherms of Argania spinosa and Zygophyllum gaetulum have, respectively a sigmoid shape (Type 2) and (Type 5). The GAB, modified Oswin, modified Henderson, Peleg, modified BET and modified Halsey models were tested to fit the experimental data. In relation to the isotherm models the best models were, GAB, modified Oswin and Peleg obtaining minor values of % mean relative errors and higher correlation coefficient. Isosteric heats of sorption were calculated through direct use of moisture isotherms by applying the Clausius-Clapeyron equation. The differential enthalpy and entropy decreased with increasing moisture content and were adequately characterized by polynomial function. A plot of differential heat versus entropy satisfied the enthalpy-entropy compensation theory. The comparison between the sorption isotherms and thermodynamic properties of A. spinosa almond and Z. gaetulum was studied.