Abstract: Mobile social network has started to influence people’s life and work way in recent years. But how to build the ever-change applications in social networks has always been the most concern question for the academic and industry. Through the analysis of Service Oriented Architecture (SOA) and social network in deeply, it developed a set of professional service components of social network and put forward an application framework of mobile social network based on SOA and cloud computing. It has explored a new approach to the research and application of social network.